New paper in Trends in Molecular Medicine

Check out my new paper with my Harvard collaborator Sean Lawler on STING for cancer immunotherapy, here!

The adaptor protein STING (STimulator of INterferon Genes) has emerged as a critical mediator of the innate immune system and a promising target for cancer immunotherapy. We carefully reviewed the current status of small molecules agonists of STING in cancer treatment, highlighting successes and limitations. Since its discovery, STING activation in cancer has shown tremendous potential in restoring anti-tumor immunity and potentiate other immunotherapies.